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04/16/24 15:09
Reason animal needs rescue: Thyroid carcinoma, confirmed with histopathology through Idexx.
Type: Medical
Date animal needs rescue by: 04/19/24
Impound type: Stray
Off stray hold: Yes
Additional notes: Junior is a friendly, ~2-3 year old neutered pitbull mix. He recently developed a large firm swelling of his throat, which was aspirated and submitted for histopathology. Histopathology is suspicious for thyroid carcinoma, which is an aggressive type of cancer. Complete removal (or at least biopsy) of the thyroid is recommended for complete diagnosis and best prognosis. This is far beyond the scope of the shelter's resources, and we do not want to leave this left untreated. Junior's best chance is being pulled by a rescue who can fundraise for a specialized surgery and chemotherapy/radiation if needed.

Histopathology Results :

INTERPRETATION:
Suspect thyroid carcinoma. See comments.

COMMENTS:
The epitheloid cells along with the location of the lesion together are most suggestive of a thyroid epithelial lineage. Most thyroid tumors in dogs are diagnosed as carcinoma despite the fact that they typically have a bland cytologic appearance; note that there is occasional more moderate anisocytosis with few mitotic figures in this case which does warrant further concern for carcinoma. Thyroid adenoma or hyperplasia cannot be completely ruled out. Thyroid epithelial cells have a neuroendocrine-like appearance which is seen in this case. Other neuroendocrine/neuroendocrine-like carcinoma or even possibly a neuroendocrine tumor such as a paraganglioma (carotid body tumor) are other considerations. No obvious evidence of metastatic disease is observed, although effacement of the lymph node cannot be discounted. Recommend evaluation for any possible mass(es) arising from the anal sac as apocrine gland adenocarcinoma of the anal sac can have a similar cytologic appearance, although this would be an unusual presentation of metastasis to a mandibular node. Additional information about the location of the mass may assist with further interpretation.

SD